There is evidence that the death rate for those infected with Covid-19 in Africa is on the increase.
And although the overall number of new cases has fallen in some countries, it remains persistently high in others, with many of these cases possibly linked to new variants of the virus.
What's happening to case numbers?
At least 40 countries have now seen a second wave of the pandemic, including all countries in the southern Africa region, says the Africa Centres for Disease Control (CDC).
"This new wave of infections is thought to be associated with the emergence of variants that are more transmissible."
A new variant of the virus - known as 501.V2 - emerged in South Africa last year, and has contributed to record case numbers in the southern African region, according to the World Health Organization (WHO).
South Africa variant: What's the risk?
"Initial analysis indicates that the variant... may spread more readily between people," according to the WHO.
However, it doesn't appear to cause more serious illness.
In South Africa itself, daily new case numbers have started to fall significantly after a second peak.
Line chart showing first and second peak in daily cases in South Africa
And because there are many more cases in South Africa than anywhere else on the continent, this has resulted in an overall fall of 17% in cases across the continent, according to the CDC.
In Nigeria, scientists have also identified a new variant of the virus, although they say there is currently no evidence to indicate it is contributing to increased transmission.
However, cases in Nigeria have been on the rise since early December, and are only just starting to trend downwards.
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